You come off as being one of those people who insists weight loss is a matter of willpower. It is not. We DO know that obesity is harmful. To speculate that these drugs that do help people lose weight like nothing else ever has might possibly cause harm is irresponsible. Any drug can cause harm, so it’s always a matter of judgment. You’re grasping at straws, and you’re out of your lane. I cannot find any study back up your claim that the drugs eventually stop working.

I would try these drugs in a heartbeat.